Quinn African Methodist Episcopalian Chapel was founded on 10 May 1858. Its first church services were held in the home of Henry Harvey. Reverend Arthur Harwell, Mr. and Mrs. Gilbert Holt, Henry and Rebecca Harvey, Retta Johnson and Jane Pogue were attendance on that first day.
Name for the African Methodist Episcopal Bishop William Paul Quinn, Quinn Chapel emphasized salvation through liberation. Many of its members were active in the Underground Railroad, including Gabriel Johnson, Perlina Pogue, Henry and Rebecca Harvey.
Within a year, the church was looking for a new home. Retta Johnson and Jane Pogue were appointed in 1859 to solicit contributions to purchase property in Ironton. On 8 April 1865, lot 668 was purchased for $191.00 from the Ohio Iron and Coal Company. The corner of 8th and Adams would become the location of Quinn Chapel.
Quinn Chapel would become the first black church in Ironton. It was a gathering place for black soldiers for the Civil War, World War I and World War II before they left to serve their country.
In June 2025, Quinn Chapel was nationally recognized as a Underground Railroad site.